Skip to content 
Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical journals and associations. We only use quality, credible sources to ensure content accuracy and integrity. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.
- 12 supplements for osteoarthritis. (n.d.).
https://www.arthritis.org/health-wellness/treatment/complementary-therapies/supplements-and-vitamins/12-supplements-for-osteoarthritis - Alluri VK, et al. (2020). An anti-inflammatory composition of Boswellia serrata resin extracts alleviates pain and protects cartilage in monoiodoacetate-induced osteoarthritis in rats.
https://onlinelibrary.wiley.com/doi/10.1155/2020/7381625 - Baden KER, et al. (2024). S-Adenosylmethionine (SAMe) for central nervous system health: A systematic review.
https://pmc.ncbi.nlm.nih.gov/articles/PMC11435340/ - Boswellia serrata. (2020).
https://www.ncbi.nlm.nih.gov/books/NBK563692/ - Brito R, et al. (2023). Chondroitin sulfate supplements for osteoarthritis: A critical review.
https://pmc.ncbi.nlm.nih.gov/articles/PMC10329866/ - Devil’s claw. (n.d.).
https://versusarthritis.org/about-arthritis/complementary-and-alternative-treatments/types-of-complementary-treatments/devils-claw/ - Goudarzi R, et al. (2018). Evaluation of the novel avocado/soybean unsaponifiable Arthrocen to alter joint pain and inflammation in a rat model of osteoarthritis.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5830030/ - Glucosamine and chondroitin for osteoarthritis: What you need to know. (2023).
https://www.nccih.nih.gov/health/glucosamine-and-chondroitin-for-osteoarthritis-what-you-need-to-know - Kim J-Y, et al. (2022). Harpagoside attenuates local bone Erosion and systemic osteoporosis in collagen-induced arthritis in mice.
https://bmccomplementmedtherapies.biomedcentral.com/articles/10.1186/s12906-022-03694-y - Kuszewski JC, et al. (2020). Fish oil supplementation reduces osteoarthritis-specific pain in older adults with overweight/obesity.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7494084/ - Leblan D, et al. (2000). Harpagophytum procumbens in the treatment of knee and hip osteoarthritis.
https://www.ncbi.nlm.nih.gov/pubmed/11143915 - Omega-3 fatty acids. (2024).
https://ods.od.nih.gov/factsheets/Omega3FattyAcids-HealthProfessional/ - Paultre K, et al. (2021) Therapeutic effects of turmeric or curcumin extract on pain and function for individuals with knee osteoarthritis: A systematic review.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7812094/ - Reginster J-Y, et al. (2020). Highly purified chondroitin sulfate: a literature review on clinical efficacy and pharmacoeconomic aspects in osteoarthritis treatment.
https://link.springer.com/article/10.1007/s40520-020-01643-8 - Salehi B, et al. Avocado–soybean unsaponifiables: A panoply of potentialities to be exploited. (2023).
https://www.mdpi.com/2218-273X/10/1/130 - SAM-e. (2022).
https://www.mskcc.org/cancer-care/integrative-medicine/herbs/sam-e - Simental-Mendía, et al. (2018). Effect of glucosamine and chondroitin sulfate in symptomatic knee osteoarthritis: a systematic review and meta-analysis of randomized placebo-controlled trials.
https://pubmed.ncbi.nlm.nih.gov/29947998/ - Sun Y, et al. (2020). Repairing effects of glucosamine sulfate in combination with etoricoxib on articular cartilages of patients with knee osteoarthritis.
https://link.springer.com/article/10.1186/s13018-020-01648-z - Toguchi A, et al. (2023). Methylsulfonymethane improves knee quality of life in participants with mild knee pain: A randomized, double-blind, placebo-controlled trial.
https://pmc.ncbi.nlm.nih.gov/articles/PMC10346176/ - MSM. (n.d.).
https://versusarthritis.org/about-arthritis/complementary-and-alternative-treatments/types-of-complementary-treatments/msm/ - Zheng L, et al. (2021). The efficacy and safety of Curcuma longa extract and curcumin supplements on osteoarthritis: A systematic review and meta-analysis.
